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Crohns Disease: Without gut microbiomes to help with digestion and to fend off infections, the body goes through persistent diarrhoea, inflammation, and a great deal of discomfort that lead to Crohns Disease

IL8 also has activating effects on polymorphonuclear cells that can drive the local environment towards inflammation

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[17] In addition, longitudinal data has shown that youth and young adults whose first use of tobacco was with a flavored product were more likely to subsequently use tobacco products